ABEMACICLIB FOR DUMMIES

mitotane will reduce the extent or outcome of abemaciclib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of abemaciclib with solid CYP3A4 inducers lowers plasma focus of abemaciclib and its metabolites.Dato-Dxd did not make severe toxicity at doses up to 200 mg/kg in rats and showed small